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Marburg virus disease (MVD) is a rare but severe hemorrhagic fever which affects both people and non-human primates. MVD is caused by the Marburg virus, a genetically unique zoonotic (or, animal-borne) RNA virus of the filovirus family. The six species of Ebola virus are the only other known members of the filovirus family.
- What Is The Marburg Virus?
- How Does The Marburg Virus Spread?
- Who Is at Risk of Marburg Virus Infection?
- How Does The Marburg Virus replicate?
- What Are The Signs and Symptoms of Marburg Virus Infection?
- How Is A Marburg Virus Infection Diagnosed?
- How Is Marburg Virus Infection Treated?
- What Are The Most Important Facts to Know About The Marburg Virus?
Marburg virus, a member of the family Filoviridae and genusMarburgvirus, is a zoonotic virus that is initially transmitted from animals to humans. Both Marburg virus and ebola virus belong to the Filoviridae family of viruses and have the capacity to cause outbreaks with high fatality rates. The animal reservoir in nature for the Marburg virus is t...
According to the World Health Organization, Marburg virus is typically transmitted to people from fruit bats through a variety of mechanisms. Infected fruit bats can spread Marburg virus to other animals (e.g., monkeys) directly or indirectly, such as through food products contaminated by fruit bats (e.g., figs, mangoes, and dates). Marburg virus i...
Individuals at risk of Marburg virus infection include those that have had close contact with Rousettus aegyptiacus African fruit bats or their secretions, such as travelers visiting caves or mines inhabited by infected bats in endemic regions of Africa. Individuals already suffering from MVD or non-human primates infected with Marburg virus may al...
The Marburg virus replicates after entering infected host cells through attachment, endocytosis, and fusion. Once the viral RNA genome of the Marburg virus is inside the infected host cell, it undergoes transcriptionand replication, after which it is released into the bloodstream where the virus continues to multiply.
Signs and symptoms of Marburg virus infection typically appear 2-21 days after exposure to the virus. Fruit bats infected with Marburg virus do not show obvious signs of illness; however, human and non-human primates infected with Marburg virusmay develop serious signs and symptoms. Early signs and symptoms of MVD are commonly characterized by the ...
Infection with the Marburg virus is typically diagnosed by a medical professional upon a thorough review of systems and medical history and conduction of a physical examination. Early detection and diagnosis of MVD can be challenging as the early signs and symptoms of MVD are non-specific and difficult to distinguish from other infectious diseases,...
Treatment of Marburg virus infection is limited to supportive care, typically after hospitalization, which includes rest, hydration, oxygen, and treatment of specific symptoms upon onset. Supportive medications include acetaminophen to relieve pain and fevers and dimenhydrinate and/or ondansetron to control nausea and vomiting. Intravenous and/or o...
Marburg virus is a zoonotic virus that is initially transmitted from animals to humans. The animal reservoir in nature for the Marburg virus are the African fruit bats. Marburg virus replicates after entering infected host cells through attachment, endocytosis, and fusion. Marburg can lead to MVD, which is a rare and severe hemorrhagic fever affect...
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Mar 23, 2023 · The Marburg virus has killed five people in north-west Tanzania. The highly-infectious disease is similar to Ebola, with symptoms including fever, muscle pains, diarrhoea, vomiting and, in some...
Apr 19, 2023 · Marburg virus disease (MVD) is a rare but severe hemorrhagic fever that affects people and non-human primates. It is caused by an infection with Marburg virus or Ravn virus, both within genus Marburgvirus. Marburgviruses are zoonotic (or, animal-borne) RNA viruses within the virus family Filoviridae. Ebolaviruses, also filoviruses, are ...
Aug 7, 2021 · Marburg virus disease (MVD), formerly known as Marburg haemorrhagic fever, is a severe, often fatal illness in humans. The virus causes severe viral haemorrhagic fever in humans. The average MVD case fatality rate is around 50%. Case fatality rates have varied from 24% to 88% in past outbreaks depending on virus strain and case management.
Marburg virus (MARV) is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species Marburg marburgvirus, genus Marburgvirus. [1] It causes Marburg virus disease in primates, a form of viral hemorrhagic fever. [2] The virus is considered to be extremely dangerous.
May 2, 2023 · 2 May 2023 | Q&A. What is Marburg virus disease? How do people become infected with Marburg virus disease? What are the typical signs and symptoms of Marburg virus disease? How long does it take to develop symptoms of Marburg virus disease? Is Marburg virus disease the same as Ebola virus disease?